Project Description
Modularize end-to-end drug manufacturing mini plants, focusing on process intensification and
improving product yield.
Investigate polymorphic transformation using a systematic design of experiments (DoE) combined with
population balance modeling (PBM)
Experience
-
• Turkish Petroleum Refineries Corporation (TUPRAS), Turkey January 2019-October
2020
Process Supervisor | Start-Up Mentor
- • Led test runs for HVGO yield improvement to meet IMO 2020 regulations.
- • Spearheaded process intensification projects during turnaround periods, resulting in a 12-point
Energy Intensity Index (EII) improvement and the successful startups of three CDU/VDU units.
- • Managed digitalization efforts for CDU/VDU and developed dynamic KPI dashboards.
- • Oversaw three data analysis projects focused on predicting bitumen penetration, applying
predictive maintenance using remaining useful lifetime (RUL), and forecasting LPG product pool
quality
based on crude oil blends and operation parameters.
-
• Turkish Petroleum Refineries Corporation (TUPRAS), Turkey March 2016-January 2019
Process Engineer
- • Monitored and optimized the product quality and energy efficiency of CDU/VDU of an annual crude
oil
capacity of 11.3 million tons.
- • Developed a dynamic tool to track heat exchanger fouling rates, simulated process
intensification
projects and performed feasibility analysis using Aspen HYSYS.
- • Led the operations side of process safety studies such as Hazard and Operability (HAZOP),
Management
of Change (MOC), Pre-Startup Safety Review (PSSR).
-
• GE Healthcare - Istanbul, Turkey July 2015-December 2015
Regulatory Affairs - Project Intern
- • Collaborated with a multinational team to coordinate premarket regulatory activities of medical
devices for regulated and unregulated countries in Africa.
- • Developed a comparison tool for medical device classification rules, which facilitated product
search in countries with different regulatory models.
-
• Teaching Assistant, Purdue University
- CHE 45000 Design and Analysis of Processing Systems Spring 2023
- • Conducted weekly teaching sessions for 50+ students to instruct them in flowsheet construction
and
optimization using Aspen Plus.
- CHE 42000 Process Safety Management & Analysis Fall 2021
- • Held office hours to assist students with their homework and graded exams for 170 students
Awards and Honors
Publications
- Akturk, I., Kilari,H., Nagy, Z. (2023). A Systematic Approach Using Model-Based
Digital Design for Polymorphic Crystallization of Imatinib Mesylate. 2023 AIChE Annual Meeting (in
prep.)
- Sundarkumar, V., Casas-Orozco, D., Akturk, I., Nagy, Z., Reklaitis, G. V. (2023).
Development of a Digital Twin for the End-to-End Continuous Manufacturing of the Cancer Drug
Lomustine. 2023 AIChE Annual Meeting (in prep.)
- Casas-Orozco, D., Mackey, J., Akturk, I., Reklaitis, G. V., & Nagy, Z. K. (2023).
Extended multiple-curve resolution framework for the calibration of first-principles models. Computer
Aided Chemical Engineering, 1439–1444.
- Chamberlain, M., Miller, J., Dowd, T., Rhim, J. S., Heflin, D., Akturk, I.,
Coffing, J., Fassnacht, M., & Mansson, J.-A. (2022). Development of a bicycle crank arm demonstrator
via industry 4.0 principles for sustainable and cost-effective manufacturing. Sports Engineering,
26(1).
Conference Presentations
- Akturk, I., Kilari,H., Nagy, Z. “Systematic Framework for Model-Based Digital
Design of Polymorphic Crystallization”, International Symposium on Industrial Crystallization (ISIC),
September 5-8, 2023, Glasgow, UK.
Education
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